HPLC and UHPLC Columns

 High Performance Liquid Chromatography Columns for Your Application

The Supelco® HPLC & UHPLC column portfolio meets today’s challenging needs of Fast HPLC, LC-MS, biopolymer separation, high pH conditions, as well as traditional pharmacopeia and agency methods within pharmaceutical, environmental, clinical, and food industries etc.

Fused-Core® technology, monolithic silica, polymeric, monodisperse silica, ultra-pure silica, and zirconia are some of the particle platforms that make up the Supelco® HPLC product line so you can find the right column for your application.

We have a tradition of providing innovative HPLC Columns; while our trusted Supelcosil, Lichrospher®, Discovery® and Purospher columns have a proven track record, our Purospher STAR and Titan™ deliver leading edge UHPLC performance at an affordable cost, and Ascentis® Express and BIOshell™ (based on Fused-Core® technology) have the capability to turn any HPLC system into a Fast HPLC workhorse. Chromolith® HPLC and UHPLC columns, based on monolithic silica, enable rapid separations at extremely low column backpressure and provide a very high matrix-tolerance making this material perfectly suitable for the separation of matrix-rich samples.

For chiral LC-MS, our Astec® chiral chromatography columns are the solution. We also supply leading brand HPLC columns, including Kromasil, TSKgel, Sepax, Hamilton and more.

If you require a custom HPLC column, please contact Supelco_Quotes@sial.com or fill out the custom HPLC column request form to obtain a quote.

  Base Material Solution for Small Molecule Separation Solution for Biomolecule Separation
Superficially porous silica particles (SPP)/Fused Core® Superficially porous silica
particles (SPP) / Fused Core®

Superficially porous silica HPLC and UHPLC columns provide very high efficiencies, which are typically 40% higher in comparison to fully porous particles of the same size.

Ascentis® Express HPLC and UHPLC columns (LC-MS, SFC)

BIOshell™ HPLC and UHPLC columns (LC-MS, SFC)

>Monolithic silica Monolithic silica
Monolithic silica HPLC and UHPLC columns enable rapid separations at very low column backpressure with very high matrix-tolerance and extended column lifetime.

Chromolith® HPLC and UHPLC columns (LC-MS, SFC)

Chromolith® WP HPLC columns (LC-MS, SFC)

Fully porous silica particles (FPP) Type B (high purity silica) Fully porous silica particles (FPP)
Type B (high purity silica)

Discovery® HPLC columns

Ascentis® HPLC columns

Purospher® STAR HPLC and UHPLC columns

Titan™ UHPLC columns (LC-MS)

SeQuant® HILIC HPLC and UHPLC columns (LC-MS, SFC)

Astec® Chiral HPLC and UHPLC columns (LC-MS, SFC)

Kromasil® HPLC columns

Discovery® BIO HPLC columns

Sepax® HPLC and UHPLC columns

Fully porous silica particles (FPP) Type A (conventional silica) Fully porous silica particles (FPP)
Type A (conventional silica)

Supelcosil® HPLC columns

LiChrospher® HPLC columns

LiChrosorb® HPLC columns

TSKgel® HPLC and UHPLC columns

Fully porous polymeric particles Fully porous polymeric particles
Enable the use of the full pH-range for
the mobile phase (0-14)

apHera™ HPLC columns

Supelcogel® HPLC columns

Hamilton HPLC columns

GE FPLC and HPLC columns

TSKgel® HPLC and UHPLC columns

Porous Graphitic Carbon (PGC) particle       
Porous Graphitic Carbon (PGC) particle-packed HPLC/UHPLC columns allow for high efficiency separations of polar compounds under reversed-phase conditions.
Supel™ Carbon LC U/HPLC Columns  
    Zirconia Particles
se Outstanding thermal and pH stability.

Discovery® Zr HPLC Columns

Other brands: ES Industries (Green Sep™ and ChromegaChiral™), Nucleosil®, Spherisorb®


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