Solid Phase Extraction

QuEChERS (Dispersive SPE)

View QuEChERS video
Introduction to Supel QuE Z-Sep
Supel™QuE Brochure - Multi-Residue Pesticide Analysis in Food and Agricultural Products Using the QuEChERS Method
Supel™ QuE Verde for Challenging Compounds in Green Matrices
Supel™ QuE Z-Sep for Fat Removal in Difficult Matrices
View the Ordering Information
We also provide Custom QuEChERS tubes/vials
View our Technical Resources
For a trial, you may request free dSPE sample MultiPaks for method development.

The “QuEChERS” (Quick, Easy, Cheap, Effective, Rugged, and Safe) method, dispersive SPE (dSPE), is a sample prep technique that has become popular in the area of multi-residue pesticide analysis in food and agricultural products.

In the QuEChERS method, food/agricultural samples are first extracted with an aqueous miscible solvent (e.g., acetonitrile) in the presence of high amounts of salts (e.g., sodium chloride and magnesium sulfate) and/or buffering agents (e.g. citrate) to induce liquid phase separation and stabilize acid and base labile pesticides. Upon shaking and centrifugation, an aliquot of the organic phase is subjected to further clean up using SPE. Unlike traditional methods using SPE tubes, in dispersive SPE, clean up is facilitated by mixing bulk amounts of SPE (e.g., Supelclean PSA, ENVI-Carb, and/or Discovery DSC-18) with the extract. After sample clean up, the mixture is centrifuged and the resulting supernatant can either be analyzed directly or can be subjected to minor further treatment before analysis.

Custom QuEChERS (Dispersive SPE) back to top
Supelco offers vials and centrifuge tubes in bulk quantities, each packed with pre-determined amounts of salts and SPE sorbents to support the most common method configurations used today. This saves the analyst the time taken to weigh out the individual materials multiple times.

Our Dispersive SPE Customization features:
  • 50 mL centrifuge tubes
  • 15 mL centrifuge tubes
  • 2 mL microcentrifuge tubes
  • Glass vials
  • A wide selection of salts, reagents, and SPE phases
Custom Quote Request
Request a Custom Quote

Technical Resources back to top
Subject No. Pages File Size Id.
View the Supel QuE Data Sheet 2 52 Kb -
Webinar: Basic Principles of Solid Phase Microextraction (SPME) Method Development - - -
Supel™QuE Brochure - Multi-Residue Pesticide Analysis in Food and Agricultural Products Using the QuEChERS Method 16 9 MB RZO
Extraction and Analysis of Neonicotinoid Pesticides from Flower Blossoms Using QuEChERS and LC-MS - - -
Improve Pigment Removal and Decrease Matrix Interferences for Pesticide Determination in Oranges Using Supel QuE Z-Sep/C18 QuEChERS Sorbent - - -
Improve Recovery for Analysis of Pesticides in Beef Kidney - - -
Increase Removal of Fat and Pigment from Avocado Extracts Prior to GC-MS Analysis of Pesticide and Metabolite Residue (Reporter US Volume 31.2) - - -
Improved Recovery of Carbendazim from Orange Juice Using QuEChERS Method - - -
Using a New High Capacity Lipid Depletion Material in Comparison to a C18 Adsorbent During Dispersive SPE Cleanup for Analysis of Veterinary Drugs in Animal Samples 21 237 Kb T411127
A New QuEChERS Dispersive SPE Material and Method for Analysis of Veterinary Drug Residue by LC-MS-MS 21 237 Kb T411098
Testing for Aflatoxins in Corn and Peanut Butter using QuEChERS Cleanup and LC Fluorescence 16 311 Kb T411097
Intralab Validation of the EN 15662 Method for the Determination of Pesticide Residues Using a Fused-Core™ Ascentis® Express RP-Amide HPLC Column by LC-MS/MS and Clean-up by Dispersive SPE (QuEChERS) (TheReporter Europe Vol. 39) 402 Kb   
Dispersive SPE (dSPE) Product Line Data/Instruction Sheet 2 37 Kb T706013
QuEChERS Multiresidue Method (overview chart) 2 218 Kb JWP
The Extraction & Analysis of Multi-Residue Pesticides in Oranges Using Dispersive SPE & GC-MS (poster) 20 196 Kb T406100
Extraction and Analyses of Agricultural Pesticides from Oranges Using the "QuEChERS" Method (TheReporter 24.3) 3 381 Kb T206003
NEW Custom “Dispersive” SPE Products for Pesticide and Acrylamide Analysis (TheReporter 23.4) 2 383 Kb T205004