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fat mass and obesity associated
Synonyms ALKBH9
Species Human (79068) , Species Mouse (26383) , Species Rat (291905) , Species Zebrafish (553363) , Species cow (618622) , Species Horse (100060565) , Species domestic cat (101098594) , Species dog (478125) , Species chicken (415718) , Species domestic guinea pig (100730858) , Species naked mole-rat (101700280) , Species sheep (100125353) , Species Domestic Rabbit (100301537)
Summary: This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]