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52776-U Supelco

SupelMIP® SPE - Patulin



Related Categories Analytical/Chromatography, Sample Preparation & Purification, Solid Phase Extraction (SPE), SupelMIP Molecular Imprinted Polymers, SupelMIP SPE - Patulin More...
composition   bed wt, 100 mg
packaging   pk of 50 ea
volume   3 mL
matrix active group   SupelMIP® phase


General description

The SupelMIP SPE line consist s of highly cross-linked polymers that are engineered to extract a single analyte of interest or a class of structurally related analytes with an extremely high degree of selectivity. This is possible because selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the analyte(s) of interest.

By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.

Visit www.sigma-aldrich.com/supelmip to learn more.


Developed for the class-selective extraction of the mycotoxin patulin from fruit, fruit products, and related sample matrices.

Features and Benefits

• Highly selective SPE for trace analysis in complex matrices
• Achieve lower detection limits
• Significant time and cost savings
• Improved MS-compatibility

Legal Information

SupelMIP is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.


Certificate of Analysis


Milli-Q® Water Purification Solutions
Protocols & Articles


Better Tools for Fast and Convenient Patulin Analysis

The mycotoxin patulin is often found in rotten apples. It is mostly produced by Aspergillus, Penicillium and Byssochlamys and shows a variety of short-term and long-term effects in animal studies, ra...
Eva Katharina Richter, Christine Dumas
Keywords: Gastrointestinal, High performance liquid chromatography, Phase transitions, Purification, Sample preparations, Separation, Solid phase extractions

Selective Extraction and Cleanup of Patulin Mycotoxin from Apple Juice Samples

Patulin (Figure 1) is a mycotoxin produced by a number of fungal species. The mold Penicillium Expansum, in particular, is known as the main source of patulin contamination1. Patulin occurrence is fo...
Olga Shimelis, K. G. Espenschied, and Jennifer Claus
Reporter US, Volume 32.1
Keywords: High performance liquid chromatography, Polymerization reactions, Sample preparations, Separation, Solid phase extractions

Selective Extraction and Low Level Quantification of the Mycotoxin Patulin from Organic Apple Puree

Patulin (Figure 1) is a mycotoxin produced by several genera of mold including blue Penicillium species. The toxin was discovered and characterized in the 1940’s during routine general research condu...
K. G. Espenschied, Olga Shimelis, Michael Ye, Jennifer Claus
Reporter US Volume 33.2
Keywords: Antibiotics, Centrifugation, Chromatography, Filtration, Gastrointestinal, Genetic, High performance liquid chromatography, Sample preparations, Solid phase extractions

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SPE Cartridges (Tubes) - Phase Selection Guide

The SPE Tube Configuraton Guide will help you choose the appropriate bed weight and cartridge dimensions.
Keywords: Agriculture, Calorimetry, Environmental, Fractionation, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pesticides, Pharmaceutical, Solid phase extractions

Solid Phase Extraction: Fundamentals and Recent Developments [Webinar]

Solid Phase Extraction (SPE) has become a popular technique for sample preparation due to its convenience, effectiveness, relatively low solvent usage and versatility. The focus of this webinar is on...
Keywords: Sample preparations, Solid phase extractions

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