• USA Home
  • 131903 - Tetraethyl orthosilicate

131903 Sigma-Aldrich

Tetraethyl orthosilicate

reagent grade, 98%

Synonym: Orthosilicic acid tetraethyl ester, Silicon tetraethoxide, TEOS, Tetraethoxysilane, Tetraethoxysilicon(IV), Tetraethyl silicate

  • CAS Number 78-10-4

  • Linear Formula Si(OC2H5)4

  • Molecular Weight 208.33

  •  Beilstein/REAXYS Number 1422225

  •  EC Number 201-083-8

  •  MDL number MFCD00009062

  •  PubChem Substance ID 24848042

  •  NACRES NA.23



Related Categories Chemical Synthesis, Materials Science, Micro/NanoElectronics, Organometallic Reagents, Organosilicon,
Quality Level   200
grade   reagent grade
vapor density   7.2 (vs air)
vapor pressure   <1 mmHg ( 20 °C)
assay   98%
form   liquid
refractive index   n20/D 1.382 (lit.)
bp   168 °C (lit.)
density   0.933 g/mL at 20 °C (lit.)
InChI   1S/C8H20O4Si/c1-5-9-13(10-6-2,11-7-3)12-8-4/h5-8H2,1-4H3



1, 2.5, 4 L in glass bottle

25, 250, 500 mL in glass bottle


Commonly used as a precursor to prepare xerogel

Will interact with dodecylamine in the formation of intercalation compounds of H+-magadiite and used in a study of mixed-metal bioactive glasses.

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Target organs 
Respiratory system
UN1292 - class 3 - PG 3 - Tetraethyl silicate
WGK Germany 
Flash Point(F) 
113.0 °F - closed cup
Flash Point(C) 
45 °C - closed cup

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
Is anything else needed to use Product 131903, Tetraethyl Orthosilicate in a hydrolysis reaction?
An acid or alkali catalyst is needed to do a hydrolysis reaction to free the silanol group for use.
What is the solubility of Product 131903, Tetraethyl Orthosilicate?
According to the 13th Edition of the chemicals encyclopedia published by the Royal Society of Chemistry, Tetraethyl Orthosilicate is practically insoluble in water and is slowly decomposed by it. It is miscible with alcohol.
Product 131903, Tetraethyl orthosilicate is commonly used as a precursor to prepare xerogel. What is xerogel?
A xerogel is a solid formed from a gel by drying with unhindered shrinkage. Xerogel usually retains high porosity and large surfaced area, along with very small pore size.
How can I purify Product 131903, Tetraethyl Orthosilicate?
Fractionate through an 80cm Podbielniak type column with heated jacket and partial take-off head. [Purification of Laboratory Chemicals Fourth Ed]
What is the freezing point of Product 131903, Tetraethyl Orthosilicate?
The freezing point is ~85°C.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
Show more questions
Protocols & Articles


Bio-Inspired “Green” Synthesis of Nanomaterials and their Applications

Dr. Siddharth V. Patwardhan Department of Chemical and Process Engineering University of Strathclyde, 75 Montrose Street Glasgow G1 1XJ, UK Email: Siddharth.Patwardhan@strath.ac.uk
Keywords: Adsorption, Agriculture, Apoptosis, Cancer, Catalysis, Condensations, Cosmetics, Deposition, Environmental, Enzyme activity, Green chemistry, Hydration reaction, Immobilization, Microwave synthesis, Nanomaterials, Pharmaceutical, Precipitation, Reductions, Separation, Sol-gel, Solvents

Nanowire Synthesis: From Top-Down to Bottom-Up

David J. Hill, James F. Cahoon* Department of Chemistry, University of North Carolina at Chapel Hill, USA *Email: jfcahoon@unc.edu
David J. Hill, James F. Cahoon*
Material Matters, 2017, 12.1
Keywords: Absorption, Catalysis, Chemical vapor deposition, Deposition, Electronics, Melting, Microelectronics, Nanomaterials, Redox Reactions, Reductions, Semiconductor

Synthesis of Melting Gels Using Mono-Substituted and Di-Substituted Alkoxysiloxanes

Hybrid organic-inorganic sol-gel materials containing silica were first called “ORMOSILs” in 1984.1 Since then, the number of hybrid organicinorganic combinations has increased rapidly.2 Hybrid mater...
Lisa C. Klein and Andrei Jitianu
Material Matters, Volume 7, Number 2, 8–14
Keywords: Absorption, Adhesion, Calorimetry, Combustion, Condensations, Deposition, Exothermic, Filtration, Materials Science, Melting, Oxidations, Polymerization reactions, Purification, Semiconductor, Sol-gel, Solar cells, Solvents, Spin coating, Substitutions, Thermal analysis

Vistas in Current Magnetic Materials Research

Magnetism and magnetic materials have been of scientific interest for over 1,000 years. More recently, fundamental investigations have focused on exploring the various types of magnetic materials and...
Keywords: Automotive, Ceramics, Detection methods, Electronics, Materials Science, Nanomaterials, Precipitation, Semiconductor

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?