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D-(+)-Glucuronic acid γ-lactone

analytical standard

Synonym: D-(+)-Glucurono-6,3-lactone, D-Glucurono-6,3-lactone, D-Glucurone, Glucuronolactone

  • CAS Number 32449-92-6

  • Empirical Formula (Hill Notation) C6H8O6

  • Molecular Weight 176.12

  •  Beilstein/REAXYS Number 83595

  •  EC Number 251-053-3

  •  MDL number MFCD00135622

  •  PubChem Substance ID 329748094

  •  NACRES NA.24

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Properties

Related Categories Additional Endogenous Metabolites Standards, Additional Standards, Analytical Standards, Analytical/Chromatography, Biomarkers and Metabolomics Standards,
Quality Level   100
grade   analytical standard
assay   ≥99.0% (sum of anomers, GC)
optical activity   [α]/D +18.8±2°, c = 8% in H2O (after 1 hr)
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
impurities   ≤0.5% water
mp   172-175 °C (lit.)
SMILES string   O=C([C@@H]([C@@H](O1)[C@H](O)[C@H](O)C1=O)O)[H]
InChI   1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h1-5,8-10H/t2-,3+,4-,5+/m0/s1
InChI key   UYUXSRADSPPKRZ-SKNVOMKLSA-N

Description

General description

D-Glucuronic acid γ-lactone is a normal human metabolite produced from glucose as starting material. It serves as a precursor for the synthesis of a number of deoxy sugars.

Application

D-Glucuronic acid γ-lactone has been used as an analytical standard for the analysis of D-glucuronic acid γ-lactone as a component of microbial extracellular polysaccharides in biofilms by high performance liquid chromatography (HPLC) with pulsed amperometric detection (PAD) as well as diode array detection (DAD). D-(+)-Glucuronic acid γ-lactone has been used as a reference standard for the determination of D-(+)-glucuronic acid γ-lactone in energy drinks by ultra-high performance liquid chromatography-triple quadrupole
tandem mass spectrometry (UHPLC-MS/MS).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
LZ8930000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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