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Corticosterone

VETRANAL®, analytical standard

Synonym: 11β,21-Dihydroxy-4-pregnene-3,20-dione, 11β,21-Dihydroxyprogesterone, 4-Pregnene-11β,21-diol-3,20-dione, Kendall’s Compound B, Reichstein’s Substance H

  • CAS Number 50-22-6

  • Empirical Formula (Hill Notation) C21H30O4

  • Molecular Weight 346.46

  •  Beilstein/REAXYS Number 2339601

  •  EC Number 200-019-6

  •  MDL number MFCD00037715

  •  PubChem Substance ID 329757087

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Application Areas and Market Segments, Biochemicals and Reagents,
Quality Level   100
grade   analytical standard
product line   VETRANAL®
assay   ≥98% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
mp   179-183 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO
InChI   1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChI key   OMFXVFTZEKFJBZ-HJTSIMOOSA-N

Description

General description

Corticosterone is one of the principal steroids secreted by the rat adrenal gland and found in rat plasma.

Application

Corticosterone may be used as a reference standard in the determination of corticosterone in plasma samples using high-performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
GM7650000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Glucocorticoids on Ascentis® C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Glucocorticoids on Ascentis® C8
Keywords: Chromatography, Clinical, High performance liquid chromatography, Hormones

HPLC Analysis of Steroids on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Steroids on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography

LC/MS/MS Analysis of Steroid Hormones in Plasma on Ascentis® Express C18 after Sample Prep using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Steroid Hormones in Plasma on Ascentis® Express C18 after Sample Prep using HybridSPE®-Phospholipid
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Hormones, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Precipitation, Separation, Solid phase extractions, Solvents

UHPLC Analysis of Corticosteroids on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Corticosteroids on Titan™ C18
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry

UHPLC/MS Analysis of Steroids on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC/MS Analysis of Steroids on Titan™ C18
Keywords: Chromatography, Mass spectrometry, Pharmaceutical

Peer-Reviewed Papers
15

References

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