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C19627 Sigma-Aldrich

Chloroacetic acid

99%

Synonym: Monochloroacetic acid

  • CAS Number 79-11-8

  • Linear Formula ClCH2COOH

  • Molecular Weight 94.50

  •  Beilstein/REAXYS Number 605438

  •  EC Number 201-178-4

  •  MDL number MFCD00002683

  •  PubChem Substance ID 57653993

  •  NACRES NA.21

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Properties

Related Categories Acids, Acids & Bases, Chemical Synthesis, Organic Acids, Synthetic Reagents More...
vapor density   3.26 (vs air)
vapor pressure   0.75 mmHg ( 20 °C)
InChI Key   FOCAUTSVDIKZOP-UHFFFAOYSA-N
assay   99%
bp   189 °C (lit.)
mp   60-63 °C (lit.)
solubility   water: soluble 3,170 g/L at 10 °C

Description

General description

Chloroacetic acid (CAA, monochloroacetic acid, MCAA) is a halogenated aliphatic carboxylic acid generally used as herbicide and preservative. Its mutagenic effects have been studied in Rattus norvegicus. The rate of degradation of MCA by photocatalysis using TiO2 at pH 3 is reported to be enhanced under the influence of ozone. It is an irritant that hydrolyzes proteins resulting in degradation of the cells. This property has been applied in treating plantar warts.

Application

Chloroacetic acid may be used to synthesize the following:
• Thiocarbamoylthioacetic acid derivatives.
• 4-Thiazolone derivatives.
• Triazinothiazolone derivatives.
• Water soluble carboxymethyl chitosan.

Packaging

1 kg in poly bottle

25 g in poly bottle

Safety & Documentation

Safety Information

Documents

Certificate of Analysis

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Protocols & Articles

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Peer-Reviewed Papers
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References

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