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C7129 Sigma-Aldrich

Citric acid monohydrate

reagent grade, ≥98% (GC/titration)

  • CAS Number 5949-29-1

  • Linear Formula HOC(COOH)(CH2COOH)2 · H2O

  • Molecular Weight 210.14

  •  Beilstein/REAXYS Number 4018641

  •  EC Number 201-069-1

  •  MDL number MFCD00149972

  •  PubChem Substance ID 24892935

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Properties

Related Categories Acids, Acids & Bases, Biochemicals and Reagents, Biological Buffers, Buffers A to Z,
grade   reagent grade
assay   ≥98% (GC/titration)
pKa    (1) 3.13, (2) 4.76, (3) 6.4
solubility   H2O: 100 mg/mL, clear, colorless (Turbidity)
SMILES string   OC(CC(O)(C(O)=O)CC(O)=O)=O.O
InChI   1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2
InChI key   YASYEJJMZJALEJ-UHFFFAOYSA-N

Description

General description

Citric acid monohydrate(CAM) is an organic acid. It can be produced by crystallization from mother liquor of citric acid solution at 20-25°C during citric acid synthesis. Its molar enthalpy of solution in water has been reported to be ΔsolHm (298.15K, m = 0.0203molkg-1) = (29061±123)Jmol-1. An investigation of its crystal growth kinetics indicates that growth is linearly dependent on size.

Application

Citric acid monohydrate may be used:
• To prepare citric acid solution employed in the acetone method of 68Ga pre-purification and radiolabeling technique.
• To prepare Tris-citrate buffer employed for the electrophoresis of bacterial enzymes.
• To improve the release of diltiazem hydrochloride from melt extruded matrix tablets.

Packaging

1 kg in poly bottle

100, 500 g in poly bottle

5 kg in poly drum

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
GE7810000
Flash Point(F) 
343.4 °F
Flash Point(C) 
173 °C

Documents

Certificate of Analysis

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Certificate of Origin

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

The Krebs cycle — harnessing chemical energy for cellular respiration

The tricarboxylic acid (TCA) cycle, also known as the Krebs or citric acid cycle, is the main source of energy for cells and an important part of aerobic respiration. The cycle harnesses the availabl...
Keywords: Addition reactions, Aerobic, Biochemistry, Catalysis, Citric Acid Cycle, Decarboxylations, Dehydration reaction, Diseases, Enzyme activity, Glycolysis, Hydration reaction, Lipid Metabolism, Mass spectrometry, Metabolism, Metabolites, Metabolomics, Oxidations, Phosphorylations, Respiration

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Peer-Reviewed Papers
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References

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