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SML1137 Sigma-Aldrich

ELN484228

≥98% (HPLC)

Synonym: 4′-Fluorobenzenesulfonanilide, N-(4-Fluorophenyl)-benzenesulfonamide, N-(4-Fluorophenyl)benzenesulfonamide, N-(p-Fluorophenyl)benzenesulfonamide, NSC 164389

  • CAS Number 312-63-0

  • Empirical Formula (Hill Notation) C12H10FNO2S

  • Molecular Weight 251.28

  •  MDL number MFCD00091019

  •  PubChem Substance ID 329825673

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, E,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
storage condition   protect from light
color   white to beige
solubility   DMSO: 20 mg/mL, clear
storage temp.   2-8°C
SMILES string   O=S(C1=CC=CC=C1)(NC2=CC=C(F)C=C2)=O
InChI   1S/C12H10FNO2S/c13-10-6-8-11(9-7-10)14-17(15,16)12-4-2-1-3-5-12/h1-9,14H
InChI key   AZORQGXJAXEIGC-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

ELN484228 is a cell penetrant α-synuclein ligand that rescues of α-synuclein induced disruption of vesicle trafficking and dopaminergic neuronal loss and neurite retraction. ELN484228 reverses a-synuclein induced impairment of phagocytosis and protects dopaminergic neurons against the toxic effects of α-synuclein A53T over-expression.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

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