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chicken
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Search Results: 5
flavin containing monooxygenase 1
Species: Human FMO1 (2326), Mouse Fmo1 (14261), Rat Fmo1 (25256), Thale Cress FMO1 (838508), cow FMO1 (508781), dog FMO1 (403604), domestic cat FMO1 (101087122), naked mole-rat Fmo1 (101709396), domestic guinea pig Fmo1 (100723945), sheep FMO1 (101105089), Domestic Rabbit FMO1 (100009120)
Gene ID:
Human(2326) flavin containing monooxygenase 1
Mouse(14261) flavin containing monooxygenase 1
Rat(25256) flavin containing monooxygenase 1
Thale Cress(838508) flavin-dependent monooxygenase 1
cow(508781) flavin containing monooxygenase 1
dog(403604) flavin containing monooxygenase 1
domestic cat(101087122) flavin containing monooxygenase 1
naked mole-rat(101709396) flavin containing monooxygenase 1
domestic guinea pig(100723945) flavin containing monooxygenase 1
sheep(101105089) flavin containing monooxygenase 1
Domestic Rabbit(100009120) flavin containing monooxygenase 1
Summary: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Jul 2008]

flavin containing monooxygenase 4
Synonyms: FMO2
Species: Human FMO4 (2329), Mouse Fmo4 (226564), Rat Fmo4 (246247), domestic guinea pig Fmo4 (100735396), naked mole-rat Fmo4 (101707236), sheep FMO4 (101105344), Domestic Rabbit FMO4 (100009119), Domestic Rabbit FMO4 (100009582), chicken FMO4 (770587), domestic cat FMO4 (101089734), cow FMO4 (539356), Horse FMO4 (100052080), dog FMO4 (490345)
Gene ID:
Human(2329) flavin containing monooxygenase 4
Mouse(226564) flavin containing monooxygenase 4
Rat(246247) flavin containing monooxygenase 4
domestic guinea pig(100735396) flavin containing monooxygenase 4
naked mole-rat(101707236) flavin containing monooxygenase 4
sheep(101105344) flavin containing monooxygenase 4
Domestic Rabbit(100009119) flavin containing monooxygenase 4
Domestic Rabbit(100009582) flavin containing monooxygenase 4
chicken(770587) flavin containing monooxygenase 4
domestic cat(101089734) flavin containing monooxygenase 4
cow(539356) flavin containing monooxygenase 4
Horse(100052080) flavin containing monooxygenase 4
dog(490345) flavin containing monooxygenase 4
Summary: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Jul 2008]

flavin containing monooxygenase 5
Species: Human FMO5 (2330), Mouse Fmo5 (14263), Rat Fmo5 (246248), Zebrafish fmo5 (794311), cow FMO5 (788719), Horse FMO5 (100065455), domestic cat FMO5 (101092533), dog FMO5 (475819), chicken FMO5 (100857694), sheep FMO5 (101113713), Domestic Rabbit FMO5 (100009064), domestic guinea pig Fmo5 (100135521)
Gene ID:
Human(2330) flavin containing monooxygenase 5
Mouse(14263) flavin containing monooxygenase 5
Rat(246248) flavin containing monooxygenase 5
Zebrafish(794311) flavin containing monooxygenase 5
cow(788719) flavin containing monooxygenase 5
Horse(100065455) flavin containing monooxygenase 5
domestic cat(101092533) flavin containing monooxygenase 5
dog(475819) flavin containing monooxygenase 5
chicken(100857694) flavin containing monooxygenase 5
sheep(101113713) flavin containing monooxygenase 5
Domestic Rabbit(100009064) flavin containing monooxygenase 5
domestic guinea pig(100135521) flavin containing monooxygenase 5
Summary: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

flavin containing monooxygenase 3
Synonyms: FMOII TMAU dJ127D3.1
Species: Human FMO3 (2328), Mouse Fmo3 (14262), Rat Fmo3 (84493), dog FMO3 (403603), domestic cat FMO3 (101089484), cow FMO3 (281167), sheep FMO3 (101104165), Domestic Rabbit FMO3 (100009065), naked mole-rat Fmo3 (101711325), domestic guinea pig Fmo3 (100727520)
Gene ID:
Human(2328) flavin containing monooxygenase 3
Mouse(14262) flavin containing monooxygenase 3
Rat(84493) flavin containing monooxygenase 3
dog(403603) flavin containing monooxygenase 3
domestic cat(101089484) flavin containing monooxygenase 3
cow(281167) flavin containing monooxygenase 3
sheep(101104165) flavin containing monooxygenase 3
Domestic Rabbit(100009065) flavin containing monooxygenase 3
naked mole-rat(101711325) flavin containing monooxygenase 3
domestic guinea pig(100727520) flavin containing monooxygenase 3
Summary: Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.[provided by RefSeq, Aug 2009]

aldo-keto reductase family 1, member C4
Synonyms: 3-alpha-HSD C11 CDR CHDR DD-4 DD4 HAKRA
Species: Human AKR1C4 (1109), cow AKR1C4 (282138)
Gene ID:
Human(1109) aldo-keto reductase family 1, member C4
cow(282138) aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]