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Search Results: 1
consortin, connexin sorting protein
Synonyms: C1orf71 PPP1R64
Species: Human CNST (163882), Mouse Cnst (226744), Rat Cnst (498297), chicken CNST (421487), dog CNST (611848), domestic cat CNST (101088971), cow CNST (541076), Horse CNST (100054634), sheep CNST (101115637), naked mole-rat Cnst (101721862), domestic guinea pig Cnst (100730837)
Gene ID:
Human(163882) consortin, connexin sorting protein
Mouse(226744) consortin, connexin sorting protein
Rat(498297) consortin, connexin sorting protein
chicken(421487) consortin, connexin sorting protein
dog(611848) consortin, connexin sorting protein
domestic cat(101088971) consortin, connexin sorting protein
cow(541076) consortin, connexin sorting protein
Horse(100054634) consortin, connexin sorting protein
sheep(101115637) consortin, connexin sorting protein
naked mole-rat(101721862) consortin, connexin sorting protein
domestic guinea pig(100730837) consortin, connexin sorting protein
Summary: Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]