Amicon® Ultra Centrifugal Filters

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Concentrate your protein, don’t lose it. Recover protein reliably when you concentrate with Amicon® Ultra filters. We’ve engineered Amicon® Ultra filters with low-binding Ultracel® regenerated cellulose membranes to ensure more precise molecular weight cut-offs. Amicon® Ultra centrifugal filters are available in four different volumes:

Unmatched performance of Amicon® Ultra filters

The video below demonstrates the clear difference between Amicon® Ultra filters and other centrifugal filters. Though the competitor device may appear to filter faster, protein is lost through the membrane.

How to select an Amicon® Ultra filter

  • Determine the starting volume of your sample
  • Determine the molecular weight (MW) of your macromolecule of interest, and choose an ultrafiltration membrane with a molecular weight cut-off (MWCO) that is 2-3 times smaller than the MW.
  • Select pack size

Protocols using Amicon® Ultra Filters

Ultrafiltration is an ideal method for concentrating, desalting, and exchanging buffers of protein samples. But did you know that you can use ultrafiltration devices for other applications, such as cleaning up labeling reactions, purifying antibodies, and removing detergents? Visit our Amicon® protein sample ultrafiltration protocol page for step-by-step protocols for using ultrafiltration membrane-based devices for a variety of applications.

Amicon® Ultra filtration products

Product number Description Maximum initial sample volume (mL) Final concentrate (retentate) volume (μL) Molecular weight cut-off (MWCO) Cart
UFC5003 Amicon® Ultra-0.5 Centrifugal Filters 0.5 15–20 3000
UFC5010 Amicon® Ultra-0.5 Centrifugal Filters 0.5 15–20 10000
UFC5030 Amicon® Ultra-0.5 Centrifugal Filters 0.5 15–20 30000
UFC5050 Amicon® Ultra-0.5 Centrifugal Filters 0.5 15–20 50000
UFC5100 Amicon® Ultra-0.5 Centrifugal Filters 0.5 15–20 100000
UFC200324 Amicon® Ultra-2 Centrifugal Filters 2 15–20 3000
UFC201024 Amicon® Ultra-2 Centrifugal Filters 2 15–20 10000
UFC203024 Amicon® Ultra-2 Centrifugal Filters 2 15–20 30000
UFC205024 Amicon® Ultra-2 Centrifugal Filters 2 15–20 50000
UFC210024 Amicon® Ultra-2 Centrifugal Filters 2 15–20 100000
UFC8003 Amicon® Ultra-4 Centrifugal Filters 4 30–70 3000
UFC8010 Amicon® Ultra-4 Centrifugal Filters* 4 30–70 10000
UFC8030 Amicon® Ultra-4 Centrifugal Filters 4 30–70 30000
UFC8050 Amicon® Ultra-4 Centrifugal Filters 4 30–70 50000
UFC8100 Amicon® Ultra-4 Centrifugal Filters 4 30–70 100000
UFC9003 Amicon® Ultra-4 Centrifugal Filters 15 150–300 3000
UFC9010 Amicon® Ultra-4 Centrifugal Filters* 15 150–300 10000
UFC9030 Amicon® Ultra-15 Centrifugal Filters 15 150–300 30000
UFC9050 Amicon® Ultra-15 Centrifugal Filters 15 150–300 50000
UFC9100 Amicon® Ultra-15 Centrifugal Filters 15 150–300 100000

*Certified for clinical applications.