Custom RNA Oligos

Standard quantities of single-stranded RNA Oligos for various applications.

Product Features

For anything marked as ‘Inquire’ below or If you have needs that are different from the other general specifications presented, please send a request to sirnarequest@sial.com.

 

Custom RNA Oligos Specifications
Scales
  • 0.05,0.2 & 1.0 µmol
  • For larger quantities & in-vivo-grade material, see our Custom iScale Oligos product
Purification
  • Desalt, Cartridge, HPLC or PAGE
  • Recommend purification for sequences >30 bases
Sequence Length
  • 7 to 45 bases (simplexes)
  • Inquire for feasibility over 45 bases
Modifications
  • Amino-Modifier C6, Amino-Modifier C7, Biotin, Cyanine 3, Cyanine 5, Cyanine 5.5, 6-FAM™, HEX™, TET™, Flipped Base, 2’-Fluoro, Inverted Abasic, 2’-OMe RNA, Phosphate, Thiol-Modifier-C6 S-S & Thiol-Modifier-C3 S-S
  • Locked Nucleic Acid available in every country outside of the United States
  • Inquire for feasibility of Locked Nucleic Acid & other modifications
Quality Control
  • 100% mass spectrometry
Format
  • Supplied dry in tubes
  • Pooling & aliquoting available (inquire for feasibility)

Minimum Yield Guarantees

Non-Modified RNA Oligos (O.D./µg)*
Scale (µmole) Desalt Cartridge HPLC PAGE
0.05 5/150 1/30 1/30 0.5/15
0.2 12/360 3/90 2.5/75 1/30
1.0 40/1,200 12/360 13/390 5/150

*Guarantees are for 20mers or longer. Oligos shorter than 20 bases will have fewer ODs. Microgram amounts are calculated based on a 30 μg/OD value. If the μg/OD value is less than 30, the reported μg value will be proportionally less. Phosphorothioated yields are 70% of the above stated values.

 

Modified RNA Oligos (O.D./µg)*
Scale (µmole) Desalt Cartridge HPLC PAGE
0.05 2/60 0.4/12 0.4/12 0.2/6
0.2 5/150 1/30 1/30 0.4/12
1.0 16/480 5/150 5/150 2/60

*Guarantees are for 20mers or longer. Oligos shorter than 20 bases will have fewer ODs. Microgram amounts are calculated based on a 30 μg/OD value. If the μg/OD value is less than 30, the reported μg value will be proportionally less. Phosphorothioated yields are 70% of the above stated values. Post-synthesis modifications may yield 50% less than the above stated values.

Shipping Schedule

Scale (µmole) Desalt Cartridge HPLC PAGE
0.05, 0.2, and 1.0 5 days 5 days 6 days 8 days

If additional help is needed, please consult our technical services group at oligotechserv@sial.com.

Materials